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LE/AF Purified Anti-Mouse CD161(NK1.1) Monoclonal Antibody
NK-1.1 surface antigen is encoded by the NKR-P1B/NKR-P1C gene, also known as CD161b/CD161c and Ly-55. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Deplete, Block,IF, IHC,FCM,IP
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Mouse IgG2a
This PK136 antibody has been reported for use in Flow Cytometric Analysis, Immunofluorescence Microscopy, Immunoprecipitation, Immunohistochemical Staining of frozen or paraffin-embedded Tissue Sections, Blocking. It has also been reported for use in cell activation , cell depletion and Complement Mediated Cell Depletion.
NK1.1
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