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LE/AF Purified Anti-Mouse CD3ε Monoclonal Antibody
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
FCM,IHC,IP,IF,WB,Block,Apop,Deplete,Activ
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Hamster IgG
This 145-2C11 antibody has been reported for use in Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections, Immunoprecipitation, Western Blotting. It has also been reported for use in cell activation and cell depletion.
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