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LE/AF Purified Anti-Human CD3 Monoclonal Antibody
CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. The OKT3 antibody is able to induce T cell activation.
FCM,IHC,Activ
Human
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Mouse IgG2a
This OKT-3 antibody has been reported for use in Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections. It has also been reported for use in cell activation.
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