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LE/AF Purified Anti-Human CD54 Monoclonal Antibody
CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.
FCM
Human
Liquid
Keep as concentrated solution.Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Whenever possible avoid freeze/thaw cycles.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Mouse IgG2a
ICAM
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