概述

产品名称：Anti-human CD45 mouse monoclonal antibody

描述：LCA (CD45) is a family of dingle chain transmembraneous glycoproteins consisting of at least four isoforms(220, 205, 190, 180kDa) which share a common large intracelluar domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicign of three exons of a single gene on chromosome 1. LCA(CD45) is expressed on cells of the human hematopoietic lineage(including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that LCA(CD45) plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed LCA(CD45).

应用范围：IHC

种属反应性：Human

免疫原：Recombinant protein of human CD45.

性能

形态：Liquid

存储条件：LCA antibody is stable for 1 month at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

存储溶液：PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol

纯度：0.2 mg/ml

亚型：Mouse IgG

应用

应用说明：IHC: 1/250-1/500 Optimal dilutions/concentrations should be determined by the end user.

图像

CD45 mouse mAb.jpg

Immunohistochemistry Staining of Human spleen with CD45 mouse mAb.